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Last Updated: 3 years ago

Possible Interaction: Ethanol and Mifepristone



Research Papers that Mention the Interaction

Systemic injection with mifepristone dose-dependently reduced alcohol SA in male and female Wistars but not in msPs.
International journal of molecular sciences  •  2021  |  View Paper
The dose of 56 mg/kg per day of MIFE produced the largest reduction in ethanol self-administration, with the average intake at 57% of baseline intakes.
The Journal of Pharmacology and Experimental Therapeutics  •  2020  |  View Paper
At the higher dose, mifepristone decreased the number of degenerating hippocampal DG cells in binge‐EtOH –treated intact animals, whereas, only a trend for reduction was observed in 15 mg/kg/day mifepristone‐treated animals in the EC, as determined by fluoro‐jade B staining.
Addiction biology  •  2014  |  View Paper
Although mifepristone produced no significant changes in behavior of EtOH-naïve animals, pretreatment with mifepristone (40 mg/kg) significantly reduced the severity of EtOH withdrawal.
Alcoholism, clinical and experimental research  •  2013  |  View Paper