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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Methylene Blue
Research Papers that Mention the Interaction
“Serum CK MB and BNP levels of alcohol group were excessively increased compared to control group (respectively p < 0.001 and p < 0.01).”
Protective effect of calpain inhibitor N-acetyl-l-leucyl-l-leucyl-l-norleucinal on acute alcohol consumption related cardiomyopathy“The inhibition of ALDH and the resulting decrease in the redox effect on the NAD system bound to alcohol dehydrogenase (EC 1.1.1.1) could explain the protective effect of methylene blue against metabolic redox effects of ethanol.”
“Whereas, co-administration of MK-801 (0.05 mg/kg), ketamine (1 mg/…-NAME, 10 mg/kg), 7-nitroindazole (7-NI, 30 mg/kg), methylene blue (10 mg/kg) as inhibitors of nitric oxide synthase (NOS), or …/cyclic-guanosine monophosphate (NO-cGMP) inhibitor, with a subeffective dose of ethanol (….”
Antidepressant-like effect of ethanol in mice forced swimming test is mediated via inhibition of NMDA/nitric oxide/cGMP signaling pathway.“In presence of ethanol , the concomitant induction of catalase (i.e. by glucose oxidase) and inhibition of aldehyde dehydrogenase (i.e. by methylene blue ) led to acetaldehyde accumulation within cells.”
“Cyanamide and methylene blue decreased the redox shift caused by ethanol and increased the rates of acetaldehyde reduction during the exchange.”
“Intravenous infusion of 1% methylene blue significantly increased the susceptibility of the mucosa to damage induced by topical 20% ethanol.”
“The maximum response induced by ethanol in control and intoxicated aortic rings with endothelium was significantly increased by treatment with eicosatetraynoic acid and methylene blue.”
“The inhibitory effects of ethanol and acetaldehyde were prevented by methylene blue , an aritificial electron acceptor.”
“Finally, the administration of methylene blue , a redox dye which oxidizes NADH2 to NAD, not only prevented the expected fall in hepatic glucose output when infused simultaneously with ethanol , but also produced a rapid restoration of hepatic glucose output previously depressed by ethanol administration in fasting dogs.”
“Methylene blue MB ) penetrates the interlayer space of GO in ethanol solution and remains intercalated after the solvent evaporation, as revealed by the expansion of the interlayer lattice and change in chemical composition.”
Intercalation of Dyes in Graphene Oxide Thin Films and Membranes
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