supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Ethanol
drug:
Methoxyflurane
Research Papers that Mention the Interaction
“Therefore, whenever xenobiotics that are substrates …, paracetamol (acetaminophen), halothane, enflurane, methoxyflurane , sevoflurane and many organic solvents (e.g. … an individual who is also chronically consuming ethanol , the accelerated metabolism of these agents and their clinical impact (e.g. …) and toxicological impact (accumulation of active metabolites) have to be considered.”
Clinical and toxicological consequences of the inductive potential of ethanol“ Methoxyflurane and ethanol inhibited uptake1.”
[Methoxyflurane and ethanol do not inhibit the neuronal uptake of noradrenaline (uptake 1) at the desipramine binding site].“The possibility that methoxyflurane increases alcohol dehydrogenase-dependent oxidation of allyl alcohol to acrolein , the proposed toxic metabolite, was evaluated by measuring the rate of acrolein formation in the presence of allyl alcohol and liver cytosol.”
“Liver/gas partition coefficients for isoflurane, enflurane, halothane and methoxyflurane increased two-fold in rats killed 16 h after a single injection of 15% ethanol 7 g kg-1.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback