Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Ethanol and Methionine





Research Papers that Mention the Interaction

After ethanol ingestion, % cum dose was significantly decreased at 60 and 120 minutes with both methionines (120 min: 10.25 +/- 1.0 vs 5.03% +/- 1.8; < 0.01 and 4.07 +/- 0.8 vs 2.16% +/- 0.9; p < 0.01, respectively).
European review for medical and pharmacological sciences  •  2008  |  View Paper
The present review describes the etiologies of these 3 vitamin deficiencies in ALD and how they interact with chronic ethanol exposure to alter hepatic methionine metabolism.
Advances in nutrition  •  2011  |  View Paper
Findings have demonstrated that ethanol feeding impairs several of the multiple steps in methionine metabolism that leads to progressive liver injury.
Seminars in liver disease  •  2009  |  View Paper
Ethanol alters hepatic methionine metabolism, leading to perturbation of S-adenosylmethionine-dependent transmethylation.
Nutrition reviews  •  2005  |  View Paper
In addition, alcohol significantly inhibited hepatic methionine synthase activity and increased homocysteine excretion in urine.
Alcohol and alcoholism  •  1999  |  View Paper
Given the toxic characteristics of acetaldehyde, methionine may prove effective in reducing the damaging effects of ethanol ingestion.
Studies with humans, given methionine doses of approximately one-tenth of those used with mice, indicated that methionine can also lower acetaldehyde in humans ingesting ethanol.
Alcoholism, clinical and experimental research  •  1989  |  View Paper
We conclude that a methionine and choline deficient diet exacerbates the effects of alcohol on methyl-group metabolism so as to produce decrements in heart carnitine not seen when alcohol is given with an adequate diet.
Alcohol  •  1987  |  View Paper
It was also demonstrated that the sulphydryl compounds β-mercaptoethylamine-HCl, cysteine and methionine significantly increased the survival rate of mice given a lethal dose of ethanol.
Biochemical pharmacology  •  1977  |  View Paper
When ethanol was fed with a diet having a methionine imbalance, the activities of acetyl CoA synthetase were depressed.
Journal of molecular and cellular cardiology  •  1977  |  View Paper
Findings in many laboratories, including ours, have demonstrated that ethanol consumption impairs several of the multiple steps in methionine metabolism that ultimately impairs the activity of many methyltransferases critical for normal functioning of the liver.
Current opinion in clinical nutrition and metabolic care  •  2013  |  View Paper
Show More