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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Increased intake of lycopene , a major carotenoid in tomatoes, consumed as the all-trans-isomer attenuates alcohol induced apoptosis in 2E1 cells and reduces risk of prostate, lung and digestive cancers.”
The role of carotenoids in the prevention of human pathologies.“These data indicate an interaction between chronic alcohol ingestion and lycopene supplementation and suggest a need for caution among individuals consuming high amounts of both alcohol and lycopene.”
High dose lycopene supplementation increases hepatic cytochrome P4502E1 protein and inflammation in alcohol-fed rats.“However, general and pathological evaluation of gastric tissues revealed that lycopene (especially at high doses) could aggravate acute gastric mucosal injury induced by ethanol.”
“Therefore, lycopene (especially at high doses) aggravates acute gastric mucosal injury caused by ethanol , but this was not due to oxidative stress or inflammatory factors.”
Lycopene Aggravates Acute Gastric Injury Induced by Ethanol
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