Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Ethanol and Limonene, (+/-)-

supplement:

Ethanol

supplement:

Limonene, (+/-)-

Research Papers that Mention the Interaction

Pretreatment of the skin with D-limonene in ethanol or D-limonene in ethanol + ultrasound significantly enhanced the iontophoretic flux of the drug in comparison to passive flux with or without pretreatment.
International journal of pharmaceutics  •  2003  |  View Paper
The transfer of ethanol to the skin is thereby enhanced under the coexistence of d-limonene in the skin.
Chemical & pharmaceutical bulletin  •  1992  |  View Paper
Therefore, ethanol may act as the accelerating agent for the promoting activity of d-limonene.
Drug design and delivery  •  1989  |  View Paper
However, d-limonene included in citrus fruits often inhibits yeast growth and makes the ethanol fermentation difficult.
AMB Express  •  2018  |  View Paper
The solubilization of R(+)-limonene was dramatically improved in the presence of the alcohol and polyols, whereas the improvement of solubilization for triglycerides containing MCT was less pronounced.
Journal of agricultural and food chemistry  •  2001  |  View Paper