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Last Updated: 4 years ago

Possible Interaction: Ethanol and Levomethadyl Acetate

Research Papers that Mention the Interaction

At 4 g/kg of ethanol , the LD50 due to LAAM was decreased to 43.9 mg/kg, showing a significant (p<0.002) potentiation of interaction toxicity between the two compounds.
Co-administration of LAAM either at 18 or 36 mg/kg significantly potentiated ethanol lethality, the LD50 due to ethanol was lowered by 21% and 36%, respectively.
Increase in toxicity with the combined administration of LAAM and ethanol was attributed in part to the retention of ethanol.
Pharmacology Biochemistry and Behavior  •  1978  |  View Paper