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Last Updated: 3 years ago

Possible Interaction: Ethanol and Levocarnitine





Research Papers that Mention the Interaction

Possible mechanisms of the protective action of L-carnitine in cases of alcohol injury are considered.
Eksperimental'naia i klinicheskaia farmakologiia  •  2004  |  View Paper
The addition of DL-carnitine (7% w/w) to diet during the administration of ethanol markedly inhibited the accumulation of triglycerides, and significantly reduced the intensity of the ethanol withdrawal syndrome.
British journal of experimental pathology  •  1977  |  View Paper
During the chronic use of alcohol the decrease of concentration of L-carnitine is marked.
The level of L-carnitine is reduced under influence of alcohol , but at the same time it suppressed also all steps of metabolism of the cells.
Georgian medical news  •  2006  |  View Paper
Ethanol treatment decreased significantly the gastric glutathione levels, and pretreatment with L-carnitine increased them significantly.
L-carnitine significantly prevented gastric ulcerogenesis induced by ethanol and decreased the ulcer index.
Plasma and gastric lipid peroxidation that was increased significantly by ethanol was decreased after treatment with L-carnitine.
Pharmacological reports : PR  •  2005  |  View Paper
We have previously … preadministration of L-carnitine to … ethanol significantly reduced fatty acid ethyl esters in different organs and that the carnitine/acylcarnitine system is crucial for maintaining a … acetyl-CoA/CoA ratio under conditions in which cellular homeostasis is exposed to the deleterious effects of accumulating organic acids.
International journal of tissue reactions  •  2002  |  View Paper
Co-administration of L-carnitine , however, increased liver microsomal CYP2E1 protein (2.5-fold) in rats given an ethanol-containing diet.
Biological & pharmaceutical bulletin  •  1993  |  View Paper