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Last Updated: 3 years ago

Possible Interaction: Ethanol and Ketoconazole



Research Papers that Mention the Interaction

Alcohol and hepatotoxic agents (for example, paracetamol, amoxicillin, ketoconazole ) should be avoided.
Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti  •  2016  |  View Paper
Production of alcohol derivatives was significantly inhibited by anti-CYP3A antibodies and by ketoconazole.
Drug metabolism and disposition: the biological fate of chemicals  •  1995  |  View Paper
Ketoconazole also dose dependently attenuated ethanol induced increase in myeloperoxidase activity and protected gastric mucosa against ethanol-induced depletion of non-protein sulfhydryl.
Research communications in molecular pathology and pharmacology  •  2003  |  View Paper
The mean residence time decreased from 0.60 +/- 0.15 (control) to 0.43 +/- 0.10 hr with ketoconazole (P less than .05) after 5 mg/kg of MPL ( free alcohol).
The Journal of pharmacology and experimental therapeutics  •  1991  |  View Paper
The increase of P-gp and CYP3A4 expression by the IO and CP ethanol extracts was inhibited by ketoconazole , an inhibitor of PXR activation.
Front. Pharmacol.  •  2017  |  View Paper