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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Results from the cell-based study indicate that the protective effects of EE were possibly due to the actions from puerarin , 3'-methoxypuerarin, daidzin, daidzein, and ononin.”
A diet formula of Puerariae radix, Lycium barbarum, Crataegus pinnatifida, and Polygonati rhizoma alleviates insulin resistance and hepatic steatosis in CD-1 mice and HepG2 cells.“Moreover, PLF and puerarin downregulated the expression of genes related to alcohol and lipid metabolism (CYP2y3, CYP3a65, ADH8a, ADH8b, HMGCRB, and FASN), endoplasmic reticulum stress, and DNA damage (CHOP, EDEM1, GADD45αa, and ATF6) and reduced levels of inflammatory factors (IL-1β, TNF-α) in zebrafish larvae.”
Puerariae Lobatae radix flavonoids and puerarin alleviate alcoholic liver injury in zebrafish by regulating alcohol and lipid metabolism.“The supplementation of puerarin can suppress these adverse effects induced by ethanol at a high dosage, as evidenced by the increased firing rate and SO2.”
“When given orally to P rats at a dose of 100 mg/kg/day, daidzein, daidzin, and puerarin decreased ethanol intake by 75%, 50%, and 40%, respectively.”
“administration of puerarin (NPI-31G), an isoflavone isolated from NPI-031 by countercurrent chromatography, significantly reduced ethanol intake in FH rats without affecting food or water intake.”
“The biotransformation efficiency of puerarin was increased 2-fold in the presence of 10% ethanol at 12 h compared to the transformation solution without ethanol.”
“Under the optimal conditions, the final conversion rate of puerarin reached 97.6±2.3% at 48 h in the presence of 10% ethanol.”
Efficient glycosylation of puerarin by an organic solvent-tolerant strain of Lysinibacillus fusiformis.
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