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Last Updated: 3 years ago

Possible Interaction: Ethanol and Insulin

supplement:

Ethanol

drug:

Insulin

Research Papers that Mention the Interaction

BACKGROUND Moderate alcohol consumption associates with lower risk of type 2 diabetes, but in postprandial studies, alcohol induced impaired insulin sensitivity.
The American journal of clinical nutrition  •  2012  |  View Paper
Consumption of 30 g/d of alcohol compared with 0 g/d reduced fasting insulin concentration by 19.2% (P =.004) and triglyceride concentration by 10.3% (P =.001), and increased insulin sensitivity by 7.2% (P =.002).
JAMA  •  2002  |  View Paper
C-peptide to insulin molar ratios were significantly higher (P < .05) in both ethanol groups at 10:00 PM and 2:00 AM than in the control group.
Metabolism: clinical and experimental  •  1995  |  View Paper
Results showed that ethanol increased plasma and hepatic triglyceride and cholesterol content, and affected plasma levels of insulin , adiponectin, leptin, and ghrelin.
Journal of food science  •  2017  |  View Paper
Further, the nutritional status is also an important component of the sometimes divergent findings pertaining to the effects of alcohol on the regulation of insulin and glucose metabolism.
Biomolecules  •  2015  |  View Paper
Chronic alcohol exposure inhibits insulin and insulin‐like growth factor signaling in the liver and brain by impairing the signaling cascade at multiple levels.
Journal of gastroenterology and hepatology  •  2012  |  View Paper
Our objective is to identify a mouse model of breast cancer whereby alcohol increases insulin sensitivity and promotes mammary tumorigenesis.
Cancer letters  •  2010  |  View Paper
Chronic ethanol consumption may improve insulin sensitivity, but the results from the randomized controlled trials are mixed.
Epidemiological studies have suggested that the relationship between ethanol and insulin sensitivity is either an inverted U-shape or a positive linear relationship.
Pharmacology & therapeutics  •  2006  |  View Paper
Ethanol and Zn(2+) were most effective when added shortly before or after insulin , indicating that all these agents facilitated cell cycle progression.
In serum-starved NIH 3T3 fibroblasts, ethanol (30-80 mM) promoted the effects of insulin and insulin-like growth factor I (IGF-I) on DNA synthesis in a Zn(2+)-dependent manner.
Of the various signal transducing events examined, ethanol stimulated cellular uptake of (45)Ca and it enhanced the stimulatory effects of insulin on p70 S6 kinase activity in a Zn(2+)-dependent manner.
The Biochemical journal  •  2000  |  View Paper
Wiping the skin gently with absolute alcohol prior to iontophoresis resulted in a 1000-fold increase in transdermal transport of insulin relative to that across untreated skin, i.e. to almost the same level as stripping the skin.
Journal of controlled release : official journal of the Controlled Release Society  •  1998  |  View Paper
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