Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Ethanol and Hydrocortisone

supplement:

Ethanol

Research Papers that Mention the Interaction

Plasma cortisol concentrations were significantly higher after concomitant alcohol and cocaine use than with cocaine alone.
The Journal of pharmacology and experimental therapeutics  •  1997  |  View Paper
One subject who was homozygous for ALDH2*2 had extraordinarily high cortisol levels at 90, 120 and 150 minutes after alcohol.
Journal of studies on alcohol  •  1994  |  View Paper
Ethanol ingestion also significantly blunted plasma cortisol levels after oCRH compared to placebo treatment.
The Journal of clinical endocrinology and metabolism  •  1993  |  View Paper
The results indicate a dose-dependency in the pharmacokinetics of both hemisuccinate and the free alcohol.
Biopharmaceutics & drug disposition  •  1985  |  View Paper
Simultaneous treatment of the animals with ethanol and hydrocortisone decreased 2-fold an inducing effect of the hormone.
Voprosy meditsinskoi khimii  •  1982  |  View Paper
Ethanol stimulated markedly biosynthesis of dipalmitoyl phosphatidyl choline in cloned rabbit lung cells; the stimulating action of ethanol was reduced very much by cortisol and less by ritodrine.
Zeitschrift fur Naturforschung. Section C, Biosciences  •  1979  |  View Paper
The anti-inflammatory effect of salicylates, hydrocortisone and ethanol may be secondary to the...
The New England journal of medicine  •  1974  |  View Paper
There may also be bidirectional impacts, such that alcohol is used as a coping mechanism and can dysregulate hypothalamic pituitary adrenal (HPA) axis functioning and cortisol.
Journal of dual diagnosis  •  2020  |  View Paper
There is an increase in the concentration of testosterone and cortisol that initiates interest in alcohol first , and then under the influence of its toxic effect, the level of these hormones decreases.
Wiadomosci lekarskie  •  2020  |  View Paper
However, the increased cortisol levels and reduced testosterone/cortisol ratio after the high ethanol dose could translate into long-term negative effects.
Medicine and science in sports and exercise  •  2014  |  View Paper
Show More