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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“The possible importance of histamine in the expression of sensitivity to alcohol is considered.”
Antihistamine blockade of alcohol-induced flushing in orientals.“Arctii Fructus water extract (AFW) or ethanol extract (AFE) and ARC reduced the production of histamine and pro-inflammatory cytokines such as interleukin (IL)-1β, IL-6, IL-8, and TNF-α in mast cells.”
“At the periphery, alcohol and acetaldehyde liberate histamine from its store in mast cells and depress histamine elimination by inhibiting diamine oxidase, resulting in elevated histamine levels in tissues.”
“In addition, alcohol affects histamine levels in the brain by modulating histamine synthesis, release, and turnover.”
“Finally, alcohol has been related with an increase of histamine levels by inhibition of diamino oxidase (DAO) and also with and increase of extracellular adenosine by inhibition of its uptake.”
“If this is the case, interaction between metabolism of histamine and putrescine and that of alcohol is likely.”
“This study suggests that histamine may be the mediator of calcitonin release following provocation by either pentagastrin or alcohol.”
“The uptake of radiolabelled histamine was also depressed by alcohol in the 2,5-''Hhistamine dihydrochloride (Amersham), and alcohol was therefore removed by freeze-drying.”
“Furthermore, this potentiating effect of high dose of histamine on the ethanol (2g/kg, i.p.)”
Central histaminergic transmission modulates the ethanol induced anxiolysis in mice“As both dopamine and histamine are known to be involved in the behavioral effects of ethanol and locomotor stimulation, these results suggest that rapid adaptations of these networks are associated with altered locomotor activity.”
“We found that ethanol upregulates key genes involved in the biosynthesis of histamine (hdc) and dopamine (th1 and th2) following a short 10-min ethanol treatment, measured by qPCR.”
“A pretreatment with L-histidine, the histamine precursor, significantly reduced ethanol-induced sedation, suggesting that brain histamine protects against the sedative effects of ethanol.”
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