Possible Interaction: Ethanol and Glycerol

“Moreover, ethanol feeding upregulated the endocannabinoid 2-arachidonoyl glycerol and its biosynthetic enzyme diacylglycerol lipase-β selectively in hepatic stellate cells and subsequently increased expression of CB1 receptors in hepatocytes of wild-type mice leading to CB1-dependent hepatic steatosis by activation of lipogenic pathways.”

“At 7°C 1.5 M glycerol decreased the erythrocytes stability against ethanol but increased the erythrocytes stability against hypotonic shock.”

“Confirming results by others, ethanol intake decreased plasma glycerol concentration and increased plasma triglycerides, especially after intake of lipid.”

“ Ethanol may offer advantages over glycerin as a scleral preservative due to its greater antibacterial activity.”

“ Ethanol inhibited gluconeogenesis from lactate by 71 ± 5% (0.5 ± 0.2 vs. 1.8 ± 0.1 …−1, 240–300 min, P < 0.001; ethanol vs. saline, P < 0.001) and from glycerol by 65 ± 6% (0.8 ± 0.2 vs. … μmol glucose · kg · min−1, P < 0.001).”

“The ability of the alcohol group of various alkanes to inhibit the binding of [3H]glycerol to C3 was also studied.”

“ Ethanol and glycerol slightly inhibited the reaction.”

“After administration of ethanol the arterial concentrations of FFA and glycerol decreased to about half, whereas the lactate concentration increased to about twice the control values, confirming other reports.”

“When ethanol is present in the blood the rate of glycerol uptake by the splanchnic organs is reduced to about one-third of the control value.”

“In rats, dermal (dorsum) application of an ethanolic copper salicylate complex (ECS) in ethanol with glycerol (Alcusal®) effectively suppressed established polyarthritis, carrageenan-induced paw oedema and the inflammatory response to hydroxylapatite microcrystals.”