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Last Updated: 2 years ago

Possible Interaction: Ethanol and Glutamine

supplement:

Ethanol

supplement:

Glutamine

Research Papers that Mention the Interaction

Ethanol activated cofilin and disrupted actin cytoskeleton, which was blocked by glutamine in an EGFR-dependent mechanism.
Ethanol down-regulated antioxidant gene expression and up-regulated cytokine and chemokine gene expression, which were blocked by glutamine in wild-type mice in the presence or absence of doxycycline, but not in EGFR*Tg mice in the presence of doxycycline.
The Journal of nutritional biochemistry  •  2019  |  View Paper
Male infants exposed to alcohol in utero were found to have reduced concentration of glutamate with glutamine (Glx) in their parietal white matter (PWM), compared to healthy male infants (p = 0.02).
Metabolic Brain Disease  •  2016  |  View Paper
Genetic biomarkers included neurotransmitter pathways associated with brain reward processes for dopaminergic (e.g., DRD2, MAOA, … (e.g., HTR3A, HTR1B, HTR3B, and SLC6A4), GABAergic (e.g., GABRA1, GABRA2, and GABRG1), glutaminergic (GAD1, GRIK3, and GRIN2C) and opioid (e.g., OPRM1, … OPRK1) pathways which presumably impact reinforcing properties of alcohol.
Gene  •  2015  |  View Paper
Our results show that addition of glutamine to culture medium significantly improved the disruption of integrity caused by ethanol , which was associated with increased expression of heat shock protein 70 (Hsp70).
Pharmacology  •  2013  |  View Paper
DT is related to an altered balance of excitatory and inhibitory amino-acid neurotransmitters, which is basically due to upregulation of glutaminergic neurotransmission induced by chronic ethanol exposure.
Srpski arhiv za celokupno lekarstvo  •  2011  |  View Paper
In the longer term, brain levels of Glu and its metabolites, such as glutamine (Gln), are likely to be chronically altered by alcohol , possibly providing a measure of overall abnormal Glu–Gln cycling.
Neuropsychopharmacology  •  2011  |  View Paper
As alcohol acts through increasing function of A-type gamma-aminobutyric acid receptors and attenuating the function of glutaminergic NMDA-receptors-related excitation, we tested whether TMS-evoked N100 response which is thought to reflect cortical inhibitory processes, might be affected by alcohol.
Journal of Neuroscience Methods  •  2007  |  View Paper
Thioctic acid or glutamine decreases ethanol intake.
International review of neurobiology  •  1960  |  View Paper
In addition, ethanol reduced glutamine synthetase activity in the 1% EtOH group.
Neurotoxicology  •  2020  |  View Paper
In all, moderate ethanol significantly inhibited glutamine absorption at the level of decreased B0AT1 expression at the brush border membrane and a reduced sodium gradient, which may contribute to malnutrition present in chronic alcoholics.
Nutrients  •  2019  |  View Paper
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