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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ethanol and Gemcitabine



Research Papers that Mention the Interaction

These data suggest that the presence of ethanol may compromise ENT1-dependent nucleoside analog drug cytotoxicity, and indeed, ethanol (5 mM) reduces the cytotoxic effects of gemcitabine (2 nM), an anti-cancer drug, in the human cancer cell line, HTB2.
Purinergic Signalling  •  2013  |  View Paper
Purpose Ethanol as an excipient is used to enhance the solubility of gemcitabine , but, sometimes, the dose of ethanol a patient may be given is much higher than the dose considered to be toxic.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners  •  2018  |  View Paper
In this study, we further investigated whether EriB or the ethanol extract of I. eriocalyx (Isodon) could potentiate the cytotoxic activity of Gem in human pancreatic adenocarcinoma cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology  •  2018  |  View Paper