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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Gaba Antagonists
Research Papers that Mention the Interaction
“The sensitivity of the GABA-IPSCs to a GABAB receptor antagonist and an agonist was decreased after chronic ethanol , suggesting that ethanol-induced neuroadaptations of GABAB receptors associated with ethanol dependence may account for the differential effects of gabapentin after chronic ethanol.”
Cellular and Behavioral Interactions of Gabapentin with Alcohol Dependence“In the present study, the … a range of recently developed GABAB receptor antagonists (phaclofen, 2-hydroxysaclofen, beta-phenyl-beta-alanine, CGP 35348) and the GABAB receptor agonist baclofen, … for their ability to block the locomotor stimulation induced by a low dose of ethanol administered IP to ….75 g/kg).”
“The effects of ethanol were antagonized by the GABA-ergic antagonist picrotoxin.”
“The cardiovascular effects of EtOH were significantly attenuated by ICV or by RVLM post treatment with ketamine (an NMDA receptor antagonist), N5-(nitroamidino)-L-2,5-diaminopentanoic acid (L-NNA; a NO synthase inhibitor), or bicuculline (a GABA receptor antagonist).”
Involvement of NMDA Receptors, Nitric Oxide, and GABA in Rostral Ventrolateral Medulla in Acute Ethanol‐Induced Cardiovascular Responses in Rats
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