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“In the pituitary gland, alcohol can decrease the production, release, and/or activity of two hormones with critical reproductive functions, luteinizing hormone and follicle-stimulating hormone.”
Alcoholism, clinical and experimental research • 2014 | View Paper
“Higher concentration of ethanol (8-50%) significantly decreased both specific hFSH and hLH binding to porcine GCs.”
“The GC suspensions and [125I]hFSH or [125I]hLH were incubated in the presence or absence of 1-… state binding was attained for 2 h at 37 degrees C. The presence of 1-4% ethanol significantly … hFSH to porcine GCs, with a maximal …, had no effect on hLH binding.”
Experimental and clinical endocrinology • 1993 | View Paper
“The pituitary levels of these hormones were similar to those of controls, but the ratios of pituitary LH and FSH to their serum levels were clearly increased after ethanol exposure, to 492% and 206.1%, respectively (p less than 0.05).”
“The prevention by alcohol of LHRH stimulation of FSH during the follicular phase suggests that alcohol may attenuate normal follicular maturation, which in turn could result in luteal phase inadequacy or anovulation, conditions often observed in alcohol-dependent women and in animal models of alcoholism.”
The Journal of pharmacology and experimental therapeutics • 1986 | View Paper
“Serum FSH concentrations tended to be higher after ethanol administration, but these differences were not significantly different from those of the saline-treated control animals.”