Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Ethanol and Folic Acid

supplement:

Ethanol

supplement:

Folic Acid

Research Papers that Mention the Interaction

A significant decrease in folic acid transport as well as expression of folate transporters was observed on ethanol treatment and the effects were reversible upon removal of ethanol.
Molecular nutrition & food research  •  2015  |  View Paper
The intestinal absorption of folic acid was decreased in binge drinking alcoholics and, prospectively, in volunteers fed alcohol with low folate diets.
The Journal of nutrition  •  2002  |  View Paper
Folate deficiency resulted an increase, whereas ethanol treatment decreased the folic acid uptake within the cells.
BioFactors  •  2015  |  View Paper
Alcohol increases urinary elimination of folic acid (6) or inhibits apical renal reabsorption of folate (7).
The Journal of nutrition  •  2015  |  View Paper
Animal and in vitro studies have suggested that alcohol may impair transport of folic acid across the placenta by decreasing expression of transport proteins.
PloS one  •  2012  |  View Paper
Conclusions:Our data provide little evidence to support a protective role for folate in ovarian carcinogenesis but suggest further evaluation of the joint effects of folic acid and alcohol is warranted.
European Journal of Clinical Nutrition  •  2011  |  View Paper
The benefits of folic acid appear strongest among persons who regularly consume alcohol , which itself is associated with risk of these cancers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology  •  2001  |  View Paper
The benefits of folic acid appear strongest among persons who regularly consume alcohol , which itself is associated with risk of these cancers.
The oncologist  •  2000  |  View Paper
Alcohol has a toxic effect on the marrow and inhibits the folic acid.
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris  •  1981  |  View Paper
The benefits of folic acid appear strongest among persons who regularly consume alcohol , which itself is associated with risk of these cancers.
American journal of epidemiology  •  1980  |  View Paper
Show More