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Last Updated: 2 years ago

Possible Interaction: Ethanol and Ezogabine



Research Papers that Mention the Interaction

Ethanol coadministration increased EZG AUC(0-∞) and C(max) by 36% and 23%, respectively.
Clinical therapeutics  •  2013  |  View Paper
Intra-LHb infusion of retigabine also reduced ethanol consumption and preference.
Neuropsychopharmacology  •  2017  |  View Paper
One of these drugs is retigabine and this study examines the effect of retigabine co-administered with ethanol on the development of alcohol dependence and the course of acute withdrawal syndrome.
Neuroscience Letters  •  2016  |  View Paper
Conclusion: Retigabine in multiple doses decreases the sensitivity of the hippocampus to an acute dose of ethanol in rabbits.
Results: Retigabine , administered as a single high or low dose, increased the depressive effect of an acute dose of ethanol on the bioelectric activity of the frontal cortex in rabbits.
The American journal of drug and alcohol abuse  •  2015  |  View Paper
Conclusions: These results indicate that the administration of retigabine may produce a decrease in ethanol consumption by rats at doses that do not significantly reduce the drinking of either water or a sucrose solution.
Results: Compared to vehicle, retigabine at a dose of 7.5 mg/kg produced a reduction in the amount of ethanol consumed.
The American journal of drug and alcohol abuse  •  2014  |  View Paper
In our previous study, retigabine reduced hippocampal changes induced by ethanol in the EEG rhythms in rabbits.
Pharmacological reports : PR  •  2020  |  View Paper