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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Ethanol coadministration increased EZG AUC(0-∞) and C(max) by 36% and 23%, respectively.”
The effects of ethanol on the pharmacokinetics, pharmacodynamics, safety, and tolerability of ezogabine (retigabine).“Intra-LHb infusion of retigabine also reduced ethanol consumption and preference.”
Ethanol Withdrawal Drives Anxiety-Related Behaviors by Reducing M-type Potassium Channel Activity in the Lateral Habenula“One of these drugs is retigabine and this study examines the effect of retigabine co-administered with ethanol on the development of alcohol dependence and the course of acute withdrawal syndrome.”
“Conclusion: Retigabine in multiple doses decreases the sensitivity of the hippocampus to an acute dose of ethanol in rabbits.”
“Results: Retigabine , administered as a single high or low dose, increased the depressive effect of an acute dose of ethanol on the bioelectric activity of the frontal cortex in rabbits.”
“Conclusions: These results indicate that the administration of retigabine may produce a decrease in ethanol consumption by rats at doses that do not significantly reduce the drinking of either water or a sucrose solution.”
“Results: Compared to vehicle, retigabine at a dose of 7.5 mg/kg produced a reduction in the amount of ethanol consumed.”
“In our previous study, retigabine reduced hippocampal changes induced by ethanol in the EEG rhythms in rabbits.”
Beneficial effect of retigabine on memory in rats receiving ethanol
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