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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Ethylmorphine
Research Papers that Mention the Interaction
“In the presence of ethanol the concentrations of several intermediate and end products of ethylmorphine and codeine changed markedly from the control situation.”
“It was concluded that all steps in the metabolism of ethylmorphine (and codeine) leading to the end products morphine-3-glucuronide and normorphine-3-glucuronide were inhibited by ethanol , and that the glucuronidation process were the ones most affected by ethanol.”
Effects of ethanol on ethylmorphine metabolism in isolated rat hepatocytes: characterization by means of a multicompartmental model.“ Ethylalcohol inhibited N-demethylation of ethylmorphine in lung and liver microsomes.”
“ Chronic ethanol treatment resulted in a significant induction of ethylmorphine and benzphetamine N-demethylase activity in both LS and SS mice with the SS selected line showing a greater (P < .05) maximal induction.”
“At low concentrations of ethanol, ethylmorphine inhibits ethanol elimination by inhibition of ADH.”
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