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Last Updated: 2 years ago

Possible Interaction: Ethanol and Epinephrine





Research Papers that Mention the Interaction

Furthermore, intoxicating effects of alcohol can be reversed by inhibiting epinephrine synthesis in the rat brain.
In the rat, the brain epinephrine concentration is reduced by alcohol , a phenomenon probably associated with both the intoxicating and rewarding effects of alcohol intake.
Annals of internal medicine  •  1987  |  View Paper
In cultured trophoblasts, EtOH treatment increased both epinephrine and 16,16'-dimethylprostaglandin E2 (dm-PGE2)-dependent cAMP production at varying ligand concentrations, suggesting an increased capacity to respond.
Biochemical pharmacology  •  1994  |  View Paper
In comatose patients (GCS less than 8) increasing ethanol levels was associated with progressively decreasing norepinephrine and epinephrine responses (p less than 0.04), such that catecholamines were reduced by 80 to 90% at ethanol concentrations approaching 400 mg/dl (87.0 mmol/l).
Alcoholism, clinical and experimental research  •  1990  |  View Paper
These findings are supported by previous studies using C14-norepinephrine and indicate that ethanol ingestion diverts the intermediate metabolism of both epinephrine and norepinephrine from the normal oxidative route to a reductive pathway.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1967  |  View Paper
epinephrine and norepinephrine … action of alcohol in dogs by Klingman and Goodall1and in man by Perman2and Abelin, Herren and Berli.3It seemed of interest to investigate further the … during the acute clinical syndromes following alcohol and drug abuse when alcohol or drug are no longer detectable in the blood.
Archives of general psychiatry  •  1960  |  View Paper
Both epinephrine and ethanol preexposure exacerbated LPS-induced liver damage and inflammation.
American journal of physiology. Gastrointestinal and liver physiology  •  2008  |  View Paper
These results may suggest a role for adrenaline synthesis in some, but not all, of the behavioral effects of ethanol.
Psychopharmacology  •  2005  |  View Paper
During the ethanol treatment the prohypertensive epinephrine effect was slightly increased.
The threshold dose for arrhythmias after epinephrine infusion (mainly 2nd and 3rd degree AV-blocks) was reduced beginning 2 days after the start of the ethanol treatment and the incidence of AV-blocks during epinephrine infusion was increased.
Archives of Toxicology  •  2005  |  View Paper
We previously determined that rats consuming nearly 9 g ethanol (EtOH) per kg body weight per day in liquid diet form for 1 week increased adrenal gene expression of enzymes for catecholamine synthesis that was further elevated by acute IMMO.
Annals of the New York Academy of Sciences  •  2004  |  View Paper
Thus, the ratio of plasma noradrenaline to adrenaline was higher during withdrawal, and this ratio also exhibited an association with the severity of ethanol withdrawal symptoms.
European journal of pharmacology  •  2002  |  View Paper
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