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Last Updated: 2 years ago

Possible Interaction: Ethanol and Eliprodil

supplement:

Ethanol

Research Papers that Mention the Interaction

In neonatal rats, antagonism of NMDA receptors during ethanol withdrawal, with drugs such as MK-801 and eliprodil , has been shown to mitigate some of the behavioral deficits induced by developmental ethanol exposure.
Neurotoxicology and teratology  •  2011  |  View Paper
Similarly, using the same experimental paradigm, oral administration of the specific polyamine receptor antagonist, eliprodil , caused a dose-related (2.0 and 5.0 mg/kg; − 30 min) inhibition of ethanol withdrawal-induced audiogenic seizure activity.
Psychopharmacology  •  2008  |  View Paper
In contrast, administration of eliprodil (in doses up to 5 mg/kg) showed only a partial, but not dose-dependent, substitution for ethanol.
European journal of pharmacology  •  1997  |  View Paper