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Last Updated: 4 years ago

Possible Interaction: Ethanol and Eicosatrienoic Acid

supplement:

Ethanol

Research Papers that Mention the Interaction

Both ethanol and carbon tetrachloride impair desaturation of linoleic acid and dihomo-gamma-linolenic acid and this appears to be relevant to the pathogenesis of fatty liver from two points of view.
Alcoholism, clinical and experimental research  •  1987  |  View Paper
Ethanol reduced the action of both GLA and DGLA possibly due to some physicochemical reaction between the alcohol and the fatty acids.
Prostaglandins, leukotrienes, and medicine  •  1985  |  View Paper
Ethanol also potentiated platelet synthesis of PGE 1 from dihomo-gamma-linolenic acid.
Ethanol also potentiated platelet synthesis of PGE1 from dihomo-gamma-linolenic acid.
Life sciences  •  1980  |  View Paper
Conversion of [1-14C] palmitic to oleic acid and eicosatrienoic to arachidonic acid were inhibited in 400 mM ethanol treated cells suggesting an inhibition of delta 9 and delta 5 desaturase activity.
Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia  •  1996  |  View Paper
Alcohol , vitamin C and chloroquine selectively enhance DGLA conversion to PGE1: opiates may either enhance of inhibit PGE1 formation selectively depending on receptor type.
Medical hypotheses  •  1980  |  View Paper
Ethanol , over the concentration range 33 to 300 mg/100 ml (7.2-65.2 x 10-3 M) caused a dose dependent and highly significant enhancement of conversion of 14C-dihomogammalinolenic acid (DGLA) to prostaglandin (PG) El and to thromboxane (Tx) B1 by human platelets.
Prostaglandins and medicine  •  1979  |  View Paper
In several models, acute ETOH exposure has been shown to stimulate the synthesis of PGE1 from dihomogamna-linolenic acid , while chronic ETOH consumption depletes microsomal arachidonate levels and presumably lowers the availability of substrate for the synthesis of PGs and related compounds of the “2” series.
Prostaglandins, leukotrienes, and medicine  •  1982  |  View Paper