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“Amitriptyline in combination with alcohol increased cumulative choice reaction times, and doxepin in combination with alcohol increased both cumulative choice reaction times and inaccuracy of reactions.”
Clinical pharmacology and therapeutics • 1975 | View Paper
“It seemed that the antianxiety effects of doxepin were to some extent antagonistic to the well- documented detrimental effect which alcohol has on the performance of these tasks.”
“Only desipramine, 5 and 10 mg/kg, metapramine, 10 mg/kg, clomipramine, 5 and 10 mg/kg and doxepin , 10 mg/kg, were able to reduce significantly the ethanol intake.”