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Last Updated: 2 years ago

Possible Interaction: Ethanol and Docetaxel

supplement:

Ethanol

Research Papers that Mention the Interaction

Higher amounts of solvents such as polysorbate 80 and ethanol in docetaxel formulation lead to severe toxicities such as febrile neutropenia, hematological, and cutaneous toxicities.
Current medical research and opinion  •  2021  |  View Paper
TxT + H/R-induced increases in IL-6, PMN infiltration and BAL-protein concentration were significantly reduced by EtOH ; however, histological morphology changes after trauma remained unaltered by EtOH.
TxT + H/R-induced systemic leukocyte activation (increased CD11b and CD31, reduced CD62L expression) as well as inflammasome activation in monocytes were significantly diminished by EtOH.
Inflammation  •  2018  |  View Paper
The ethanol used to prepare solid dispersion is of more significant effect on the dissolution of docetaxel than that of acetone.
Drug development and industrial pharmacy  •  2008  |  View Paper