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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Diprenorphine
Research Papers that Mention the Interaction
“ Diprenorphine increased rats' intake of the ethanol solution compared to placebo.”
Selected opioids, ethanol and intake of ethanol.“Incubation with 200 mM ethanol for 48 hr increased [3H]diprenorphine binding by 1.4- (N18TG2), 1.8- (NG108-15), 1.9- (N4TG1), and 3.0-fold (N1E-115).”
Ethanol increases delta-opioid receptor gene expression in neuronal cell lines.“Naltrexone (2-16 mg/kg) and naloxone (2-16 mg/kg) were not able to attenuate effects of ethanol, while diprenorphine decreased ethanol sleeping time (4 microgram/kg) and antagonized the ethanol hypothermia (8 microgram/kg).”
“We studied the ability of opioid antagonists: naloxone, naltrexone and diprenorphine and an opioid agonist morphine to influence the effects of ethanol on hypothermia, sleeping time and impairment of aerial righting reflex.”
“We found that naloxone, naltrexone and diprenorphine modified the ethanol withdrawal syndrome.”
“ Diprenorphine , across a wide range of doses, increased intake of ethanol solution.”
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