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Last Updated: 2 months ago

Possible Interaction: Ethanol and Dihydroxyphenylalanine

Research Papers that Mention the Interaction

of ethanol significantly increased the levels of L-DOPA to 60% above the control value.
European journal of pharmacology  •  2005  |  View Paper
Ethanol caused a dose-dependent accumulation of DOPA in the corpus striatum after inhibition of DOPA-decarboxylase suggesting an increased synthesis of DA.
Journal of Neural Transmission  •  2005  |  View Paper
Administration of ethanol and L-dopa, as compared to the administration of L-dopa only, markedly increased brain levels of dopa and dopamine.
Journal of neuroscience research  •  1987  |  View Paper
Injection of 3-O-methyl dopa at acidic pH or 0.1 N HCl, but not the same drug dosage at neutral pH or saline, resulted in reduction of voluntary drinking of ethanol by the male rat.
Neurobehavioral toxicology and teratology  •  1985  |  View Paper
Abstract Acute oral administration of ethanol (3.2g/kg) to normal rats increased DOPAC levels and DOPA formation in the caudate nucleus but had no effect in the substantia nigra and frontal cortex and failed to modify dopamine (DA) levels in any of the above brain areas.
Life sciences  •  1980  |  View Paper
A single oral administration … 3.2 g/kg ethanol to normal rats increased 3,…-dihydroxyphenylacetic acid (DOPAC) content and DOPA formation in the caudate nucleus but had no effect in frontal cortex and substantia nigra and did not modify dopamine (DA) levels in any of the brain regions analyzed.
Bollettino della Societa italiana di biologia sperimentale  •  1980  |  View Paper
Eight hours after a single (3 g/kg) dose of ethanol, DOPA synthesis was increased and pimozide, a dopamine receptor antagonist, stimulated DOPA synthesis to the same degree in ethanol-treated and control animals.
Journal of neurochemistry  •  1978  |  View Paper