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Last Updated: 2 years ago

Possible Interaction: Ethanol and Dihydrotestosterone

Research Papers that Mention the Interaction

We … that ethanol and ethyl acetate extracts from C. … and G. lucidum, respectively, selectively inhibit dihydrotestosterone-induced LNCaP cell viability, suppress levels of secreted prostate-specific antigen in a dose-dependent manner, and cause a G1 phase arrest in LNCaP, but not in DU 145 and PC-3 cells.
Molecular Biology Reports  •  2007  |  View Paper
UNLABELLED In our previous study we showed that alcohol disturbed the circadian rhythms of LH, testosterone and its conversion to DHT.
Endokrynologia Polska  •  1992  |  View Paper
The amount of alcohol consumed during the day before the blood and saliva sampling shows a significant effect on the DHT metabolism, and the shorter the time after drinking, the greater decrease of DHT and DHT/E2 can be observed.
American journal of physical anthropology  •  1991  |  View Paper
These observations indicate that dihydrotestosterone has a direct suppressant effect on hepatocyte alcohol dehydrogenase and that the enzyme activity is a major determinant of the rate of ethanol elimination.
Biochemical pharmacology  •  1986  |  View Paper
Dihydrotestosterone was found to be a substrate of liver alcohol dehydrogenase in the reductive direction and a competitive inhibitor of ethanol oxidation by the enzyme.
Hepatology  •  1982  |  View Paper