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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Diclofenac
Research Papers that Mention the Interaction
“ Ethanol at a concentration of 3.0 vol% (510 mM) increased the K(m) value of diclofenac metabolism without changes in the V(max), which indicates that diclofenac 4'-hydroxylation by CYP2C9.1 was competitively inhibited by ethanol.”
Effect of ethanol on S-warfarin and diclofenac metabolism by recombinant human CYP2C9.1.“The addition of benzyl alcohol , a preservative, in oil drops, increased the Papp value of diclofenac.”
In vitro corneal permeation of diclofenac from oil drops.“Higher P and removal of DCF (28.24 ± 1.10%) and IBU (18.72 ± 1.60%) with ethanol was observed for 43.20 ± 0.01 mgDCF L-1 and 43.42 ± 0.03 mgIBU L-1, respectively.”
Methanogenic potential of diclofenac and ibuprofen in sanitary sewage using metabolic cosubstrates.
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