supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Ternary phase diagrams of DEET with water and semipolar solvents, ethanol , PG and PEG 400, showed an increase in the aqueous solubility of DEET.”
“This study clearly demonstrates that alternative formulations can be developed for DEET aimed at reduced permeation and toxicity unlike the current formulations some of which contain ethanol which has been shown to enhance permeation of DEET.”
Reduction in skin permeation of N,N-diethyl-m-toluamide (DEET) by altering the skin/vehicle partition coefficient.“Therefore, there is potential for significant absorption of DEET after the dermal application of commercial mosquito repellents, and ethanol , used as a solvent, may enhance the permeation of DEET.”
“In contrast, a less subtype-selective agonist, (+)-4-[(αR)-α-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N N-diethylbenzamide (SNC80), while also reducing anxiety-like behavior, increases ethanol consumption.”
Dual Efficacy of Delta Opioid Receptor-Selective Ligands for Ethanol Drinking and Anxiety“ Ethanol enhances the absorption of paraquat, DMF, and DEET in a dose-dependent fashion.”
“ Ethanol is a known penetration enhancer and would ideally not be used in a formulation containing DEET , a compound known for its potential toxicity.”
Topical formulation studies with DEET (N,N-diethyl-3-methylbenzamide) and cyclodextrins.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback