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Last Updated: 5 days ago

Possible Interaction: Ethanol and Cytisine

supplement:

Ethanol

Research Papers that Mention the Interaction

In addition, cytisine (0.5 mg/kg) significantly attenuated up-regulation of ΔFosB in the ventral and dorsal striatum following chronic ethanol consumption in IA and CA paradigms.
Pretreatment with cytisine (0.5 or 1.5 mg/kg) significantly reduced ethanol consumption and preference in both paradigms at 2 h and 24 h post-treatment.
Alcohol  •  2013  |  View Paper
Pre-clinical and clinical studies have shown that neuronal nicotinic acetylcholine receptor (nAChR) partial agonists such as cytisine and its derivative, varenicline, reduce alcohol (ethanol) consumption and seeking behavior.
Pretreatment with varenicline (0.5 or 3.0 mg/kg) or cytisine (0.5 or 3.0 mg/kg) significantly reduced the expression of ADE at 4 h and 24 h after ethanol re-exposure.
Pharmacology Biochemistry and Behavior  •  2013  |  View Paper
significantly reduced ethanol consumption post 1-h, 2-h, 4-h and 12-h treatment and pretreatment with cytisine (0.5, 1.5 or 3mg/kg, s.c.)
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  2011  |  View Paper
Nicotinic agonists, cytisine and nicotine, reduced ethanol consumption.
Psychopharmacology  •  2009  |  View Paper