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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Surprisingly, ethanol intake combined with creatine exacerbated cell degeneration and fat accumulation, hepatic expression of genes related with ethanol metabolism, oxidative stress and inflammation, and promoted oxidative stress and elevated plasma alanine aminotransferase (P < 0.05).”
Creatine supplementation exacerbates ethanol-induced hepatic damage in mice.“The worsening liver pathology could be related to the profound reduction in the hepatic methylation index, an increased accumulation of GAA and the inability of creatine generated to exert its hepato-protective effects in the setting of ethanol.”
“The choline: creatine ratio detected by 1H-MRS in the brain increased significantly with increasing duration of in utero ethanol exposure.”
“The chronic action of alcohol also reduces the respiratory activation by creatine (%Cr) which ranks among the most sensitive indicators of mitochondrial respiration regulation by creatine kinase.”
“ Ethanol and other drugs of abuse disrupt learning and memory processes, creating problems associated with drug use and addiction.”
Adult and adolescent C57BL/6J and DBA/2J mice are differentially susceptible to fear learning deficits after acute ethanol or MK-801 treatment
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