Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Ethanol and Colforsin



Research Papers that Mention the Interaction

When ethanol (5%) was given along with TSH, sodium fluoride, Gpp(NH)p, or forskolin , there was a greater increase in AC activity than when no alcohol was present.
World Journal of Surgery  •  2005  |  View Paper
Ethanol treatment enhanced intracellular adenosine 3':5'-cyclic monophosphate (cAMP) levels in response to either cholera toxin (CTX) or forskolin (FSK).
Biochemical pharmacology  •  1998  |  View Paper
Forskolin had no effect on the ethanol ratio at either 1.0 microM or 10 microM, while forskolin at 100 microM induced a significant decrease in the ethanol ratio.
Pharmacology & toxicology  •  1997  |  View Paper
Furthermore, EtOH increased the stimulation of P4 secretion by Forskolin.
Alcoholism, clinical and experimental research  •  1994  |  View Paper
Preincubation of platelets with agents that increase levels of cAMP (i.e., forskolin , prostacyclin) inhibited these responses to ethanol in a concentration- and time-dependent manner.
Thrombosis research  •  1990  |  View Paper
In addition, ethanol significantly reduced the forskolin-induced increase in cAMP content in SMG in vitro while treatment with AM251 blocked this response.
Alcohol and alcoholism  •  2009  |  View Paper
AEA and EtOH reduced forskolin-stimulated LHRH release, but AM251 significantly blocked that inhibition.
Proceedings of the National Academy of Sciences of the United States of America  •  2004  |  View Paper
The ethanol extracts of each of the three plants partially reduced the current stimulated by forskolin.
Journal of pharmacological sciences  •  2004  |  View Paper
The intestinal epithelia were activated with current raised by serosal administration of forskolin 5 microM. Ethanol extracts of the three plants all augmented the current additively when each was added after forskolin.
Biological & pharmaceutical bulletin  •  2004  |  View Paper
Ethanol also reduced ATP levels in isolated gastric glands and in cultured parietal cells (EC(50): 8.8 +/- 0.4% and 8.5 +/- 0.2%, respectively) and decreased both basal and forskolin-stimulated cAMP levels.
American journal of physiology. Gastrointestinal and liver physiology  •  2001  |  View Paper
Show More