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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“When ethanol (5%) was given along with TSH, sodium fluoride, Gpp(NH)p, or forskolin , there was a greater increase in AC activity than when no alcohol was present.”
Effect of ethyl alcohol on the TSH-receptor-cyclase system in thyroid and nonthyroid tissues“ Ethanol treatment enhanced intracellular adenosine 3':5'-cyclic monophosphate (cAMP) levels in response to either cholera toxin (CTX) or forskolin (FSK).”
“Forskolin had no effect on the ethanol ratio at either 1.0 microM or 10 microM, while forskolin at 100 microM induced a significant decrease in the ethanol ratio.”
“Furthermore, EtOH increased the stimulation of P4 secretion by Forskolin.”
“Preincubation of platelets with agents that increase levels of cAMP (i.e., forskolin , prostacyclin) inhibited these responses to ethanol in a concentration- and time-dependent manner.”
“In addition, ethanol significantly reduced the forskolin-induced increase in cAMP content in SMG in vitro while treatment with AM251 blocked this response.”
Role of the endocannabinoid system in ethanol-induced inhibition of salivary secretion.“AEA and EtOH reduced forskolin-stimulated LHRH release, but AM251 significantly blocked that inhibition.”
“The ethanol extracts of each of the three plants partially reduced the current stimulated by forskolin.”
“The intestinal epithelia were activated with current raised by serosal administration of forskolin 5 microM. Ethanol extracts of the three plants all augmented the current additively when each was added after forskolin.”
“ Ethanol also reduced ATP levels in isolated gastric glands and in cultured parietal cells (EC(50): 8.8 +/- 0.4% and 8.5 +/- 0.2%, respectively) and decreased both basal and forskolin-stimulated cAMP levels.”
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