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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Ethanol
supplement:
Cocoa Extract
Research Papers that Mention the Interaction
“Additionally, enteral ethanol caused severe fat accumulation, mild inflammation, and necrosis in the liver; cocoa extract significantly blunted these changes.”
“After 4 weeks, serum alanine amino transferase levels of the ethanol group were increased nearly fourfold (110+/-16 IU/L) compared to control values (35+/-3 IU/L); this effect of ethanol was blocked by cocoa extract (60+/-6 IU/L).”
“Further, ethanol significantly increased the accumulation of protein adducts of 4-hydroxynonenal, a product of lipid peroxidation serving as an index of oxidative stress; again this was counteracted by the addition of cocoa extract.”
“Increases in liver TNFalpha protein levels caused by ethanol were completely blocked by cocoa extract.”
Cocoa extract protects against early alcohol-induced liver injury in the rat.
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