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Last Updated: 3 years ago

Possible Interaction: Ethanol and Cocoa Extract

supplement:

Ethanol

supplement:

Cocoa Extract

Research Papers that Mention the Interaction

Additionally, enteral ethanol caused severe fat accumulation, mild inflammation, and necrosis in the liver; cocoa extract significantly blunted these changes.
After 4 weeks, serum alanine amino transferase levels of the ethanol group were increased nearly fourfold (110+/-16 IU/L) compared to control values (35+/-3 IU/L); this effect of ethanol was blocked by cocoa extract (60+/-6 IU/L).
Further, ethanol significantly increased the accumulation of protein adducts of 4-hydroxynonenal, a product of lipid peroxidation serving as an index of oxidative stress; again this was counteracted by the addition of cocoa extract.
Increases in liver TNFalpha protein levels caused by ethanol were completely blocked by cocoa extract.
Archives of biochemistry and biophysics  •  2002  |  View Paper