Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Ethanol and Clomipramine

supplement:

Ethanol

Research Papers that Mention the Interaction

Nortriptyline enhanced the deleterious effect of alcohol on the ability to learn new material, whereas chlorimipramine antagonized alcohol in this respect.
Psychopharmacologia  •  2004  |  View Paper
It seems as if doxepin and amitriptyline but not nortriptyline or chlorimipramine , in combination with 0.5 gm/kg of alcohol , may be especially dangerous in driving.
Clinical pharmacology and therapeutics  •  1975  |  View Paper
Significant potentiation of ethanol excitation was seen with 500 nM clomipramine , but not at higher or lower concentrations.
The Journal of pharmacology and experimental therapeutics  •  1996  |  View Paper
Furthermore, blocking the serotonin uptake by clomipramine 5 mg X kg-1 or 10 mg X kg-1 also reduces voluntary intake of ethanol.
Pharmacology Biochemistry and Behavior  •  1985  |  View Paper
Only desipramine, 5 and 10 mg/kg, metapramine, 10 mg/kg, clomipramine , 5 and 10 mg/kg and doxepin, 10 mg/kg, were able to reduce significantly the ethanol intake.
Alcohol  •  1984  |  View Paper