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Last Updated: 3 years ago
supplement:
Ethanol
supplement:
Chymotrypsin
Research Papers that Mention the Interaction
“By either route, ethanol administration substantially reduced volume, concentration and output of bicarbonates, lipase and chymotrypsin.”
Inhibitory action of alcohol on human exocrine pancreatic secretion“ Ethanol and in higher degree acetaldehyde displayed inhibitory effect directed against amidolytic activity of trypsin and chymotrypsin.”
“Moreover, there was a significant correlation between the mean inhibition of chymotrypsin output and the mean increase in PP plasma levels during the first 45 min following ethanol infusion.”
“… ethanol … chymotrypsin ; (b) a concomitant direct effect on the sphincter of Oddi that would increase sphincteric resistance with resultant increase in intrapancreatic ductal pressure; (c) ductal … these observations, many of them made in experimental animals, the mode of production of alcoholic pancreatitis is still debatable and requires further investigation.”
“ Ethanol caused a doubling in the carbachol-induced activation of the proteases trypsin and chymotrypsin (p < 0.02).”
Ethanol Enhances Carbachol-induced Protease Activation and Accelerates Ca2+ Waves in Isolated Rat Pancreatic Acini*“Abstract The protection of α-chymotrypsin from denaturation by ethanol and urea by hydrocinnamic acid is reported.”
The Protection of Alpha-Chymotrypsin by Hydrocinnamate from Denaturation by Ethanol and Urea
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