Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Ethanol and Chenodeoxycholate



Research Papers that Mention the Interaction

Treatment with chenodeoxycholic acid , which suppresses abnormal bile acid synthesis in these patients, reduced plasma bile alcohol concentrations dramatically.
Journal of lipid research  •  1987  |  View Paper
The BA levels, especially the toxic BAs chenodeoxycholic acid , deoxycholic acid and lithocholic acid), in the whole EHC were significantly increased by ethanol intake, which may provide a potential explanation to illuminate the pathogenesis of alcoholic liver injury.
Alcohol and alcoholism  •  2020  |  View Paper
Furthermore, our data show that ursodeoxycholic acid still exerts its beneficial effects in a model of more severe hepatic intoxication induced by the co-administration of ethanol and chenodeoxycholic acid.
The … to chronic ethanol feeding (28 …) with chenodeoxycholate , a hydrophobic bile salt, aggravated steatosis (accumulation of triacylglycerols and cholesterol esters), lipoperoxidation and cytolysis (expressed as elevations of activities of aspartate aminotransferase and glutamate dehydrogenase), while the addition of ursodeoxycholic acid, a hydrophilic bile salt, alleviated ethanol-induced hepatic alterations.
Alcohol and alcoholism  •  2002  |  View Paper
Ethanol consumption prolonged the half-excretion time of labeled cholic or chenodeoxycholic acids , increased slightly the pool size, and decreased daily excretion.
Journal of lipid research  •  1972  |  View Paper