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Last Updated: 3 years ago

Possible Interaction: Ethanol and Cefamandole

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supplement:

Ethanol

drug:

Cefamandole

Research Papers that Mention the Interaction

“Several reports have described an unpleasant disulfiramlike reaction to alcohol experienced by patients taking cephalosporin antibiotics such as cefamandole (CMD), cefoperazone and moxalactam (1-4).”

Inactivation of aldehyde dehydrogenase by a putative metabolite of cefamandole re:K. J. Freundt et al. Infection 13 (1985) 91

Infection • 2005 | View Paper

“Disulfiram, cefamandole , and procarbazine significantly increased blood acetaldehyde levels after ethanol administration, while on the contrary, cotrimoxazole, griseofulvin, and propranolol had no effect on blood acetaldehyde.”

Increased Brain Serotonin Rather Than Increased Blood Acetaldehyde as a Common Denominator Behind Alleged Disulfiram-Like Reactions

International journal of toxicology • 2020 | View Paper

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