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“Maximum plasma concentrations for the R(+) and S(−) carvedilol enantiomers were similar except when ethanol was ingested 2 hours after carvedilol controlled‐release administration, where there was a modest decrease in maximum plasma concentration for R(+) and S(−) carvedilol (16% and 17%, respectively).”
Journal of clinical pharmacology • 2007 | View Paper
“The flux of carvedilol from Transcutol, Labrasol, polyethylene glycol 400, ethanol , and oleic acid was 10.5, 8.6, 4.2, 2.9, and 1.5 times higher, respectively, than that observed with control.”