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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Carbenoxolone
Research Papers that Mention the Interaction
“4 The carbenoxolone (200 mg kg−1, p.o.)‐induced gastroprotection against ethanol was antagonized by l‐NNA (5–40 mg kg−1) in a dose‐dependent manner.”
Effect of carbenoxolone on the biological activity of nitric oxide: relation to gastroprotection“Significantly, the pre-treatment with PGE2 or CBX prevented the gastric ulcer damage promoted by indomethacin or ethanol , respectively.”
The pathophysiology of acute gastric ulcer development in normotensive and hypertensive rats: A comparative study.“The PD reduction induced by indomethacin + ethanol (20%) was clearly prevented by PGE2 or carbenoxolone , as well as by isoproterenol or i.v.”
“The lipoxygenase inhibitor nordihydroguaiaretic acid (NDGA) and the anti-ulcer drug carbenoxolone CX ) inhibited mucosal release of LTC4 and simultaneously protected against gastric damage caused by ethanol.”
“Maximum inhibition of lesion formation occurred when carbenoxolone was administered 15 min before ethanol.”
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