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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Patients with a history of alcohol or chemical abuse were significantly less likely to respond to bupropion.”
Bupropion Sustained-Release for the Treatment of Dysthymic Disorder: An Open-Label Study“ Bupropion , 100 mg, had no effect alone but abolished the sedation and auditory vigilance impairment produced by alcohol when co-administered.”
“Combination of the top alcohol dose with bupropion , however, produced a significant reversal with lowered energy in the 4–7.5 Hz band.”
“Combination of bupropion with alcohol failed to change the blood alcohol concentration achieved.”
“An expert report attributed the aggressive outburst to an interaction between bupropion and alcohol ; the accused was a social drinker and had never been violent.”
“Acetonitrile, DMSO, and ethanol were shown to increase the Km and decrease the intrinsic clearance (CLint) of CYP2B6-mediated bupropion hydroxylation in a concentration-dependent manner.”
“Combination of the top alcohol dose with bupropion , however, produced a significant reversal with lowered energy in the 4–7.5 Hz band.”
“Combination of bupropion with alcohol failed to change the blood alcohol concentration achieved.”
“A fatality due to the ingestion of bupropion and ethanol is presented.”
“Pretreatment with ethanol produced a larger bupropion HCl-induced convulsive effect at all the doses (70% each at 100, 110 and 120 mg/kg) and a 10% effect in the ethanol + vehicle only group.”
Alcohol significantly lowers the seizure threshold in mice when co-administered with bupropion hydrochloride
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