Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago

Possible Interaction: Ethanol and Bortezomib

supplement:

Ethanol

Research Papers that Mention the Interaction

The beneficial effects of proteasome inhibitor treatment against oxidative stress occurred because antioxidant response elements (glutathione peroxidase 2, superoxide dismutase 2, glutathione synthetase, glutathione reductase, and GCLC) were up-regulated when rats fed alcohol were treated with a low dose of PS-341 ( Bortezomib , Velcade(®)).
World journal of gastroenterology  •  2011  |  View Paper
Bortezomib (BRZ) treatment at non-toxic doses of rats fed alcohol chronically has shown protective effects by increasing liver antioxidant enzymes.
Experimental and molecular pathology  •  2013  |  View Paper
The proteasome inhibitor Velcade attenuated atrophy produced by EtOH + disuse.
Alcoholism, clinical and experimental research  •  2008  |  View Paper