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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Ethanol and Betulinic Acid



Research Papers that Mention the Interaction

Fed-batch cultivations with ethanol excess, using either an ethanol-pulse feed or controlling a constant ethanol concentration in the fermentation medium, significantly enhanced production of betulinic acid and its triterpenoid precursors.
Biotechnology and bioengineering  •  2017  |  View Paper
Administration of BA or BT significantly decreased CYP2E1 activities and expression of SREBP-1caused by ethanol , however, lower dosage of BA or BT showed slight effects on CYP2E1 activity or expression of SREBP-1c.
Administration of BA or BT significantly prevented the increases of serum ALT and AST caused by ethanol , as well as serum TG.
International immunopharmacology  •  2013  |  View Paper
BA pretreatment significantly reduced the serum levels of alanine transaminase, aspartate transaminase, total cholesterol, and triacylglycerides in a dose-dependent manner in the mice administered alcohol.
Journal of veterinary science  •  2014  |  View Paper
However, both betulin and betulinic acid inhibited the production of ROS by HSCs treated with ethanol and inhibited their migration as well as ethanol-induced TNF-α, and TGF-β1, production.
Toxicology  •  2011  |  View Paper