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Last Updated: 3 years ago

Possible Interaction: Ethanol and Beta Carotene




Beta Carotene

Research Papers that Mention the Interaction

By contrast, beta-carotene , a precursor of vitamin A, was considered innocuous until recently, when it was found to also interact with ethanol , which interferes with its conversion to retinol.
Furthermore, the combination of beta-carotene with ethanol results in hepatotoxicity.
Moreover, in smokers who also consume alcohol, beta-carotene supplementation promotes pulmonary cancer and, possibly, cardiovascular complications.
Thus ethanol , while promoting a deficiency of vitamin A also enhances its toxicity as well as that of beta-carotene.
The American journal of clinical nutrition  •  1999  |  View Paper
Alcohol also alters the degradation of key nutrients, thereby promoting deficiencies as well as toxic interactions with vitamin A and beta carotene.
Gastroenterology  •  1994  |  View Paper
Alcohol also alters the degradation of key nutrients, thereby promoting deficiencies as well as toxic interactions with vitamin A and beta-carotene.
Journal of toxicology. Clinical toxicology  •  1994  |  View Paper
In rats and baboons, the hepatotoxicity of chronic ethanol consumption is exacerbated by beta-carotene feeding , but the mechanism of this adverse effect is unknown.
Alcohol and alcoholism  •  2001  |  View Paper
Beta-carotene plus alcohol accounted for 28.1% (95% CI = 16.8-39.4) of the cases.
Journal of the National Cancer Institute  •  1998  |  View Paper
Multiple linear regression analysis controlling for age, serum total cholesterol, serum triglycerides, … of green vegetables, yellow vegetables and fruit, showed that both smoking and alcohol had a … levels of beta‐carotene and alpha‐carotene; only smoking reduced the level of … alcohol significantly affected the level of lycopene or zeaxanthin.
Japanese journal of cancer research : Gann  •  1996  |  View Paper
These results suggest that plasma levels of beta-carotene among smokers and, perhaps, heavy consumers of alcohol may be reduced substantially below levels due to differences in diet.
American journal of epidemiology  •  1988  |  View Paper
In addition, ethanol consumption caused age-dependent decreases in the levels of GSH, selenium, vitamins, E, A and C, and beta-carotene and increases in the levels of oxidized glutathione (GSSG).
Alcohol  •  2005  |  View Paper
BACKGROUND Hepatotoxicity of ethanol is increased by beta-carotene in both rodents and nonhuman primates.
CONCLUSIONS Be a-carotene po tentiates the CYP2E1 induction by eth anol in rat liver and also increases CYP4A1, which may, at least in part, explain the associated hepatotoxicity.
Alcoholism, clinical and experimental research  •  2001  |  View Paper
Ethanol seems to affect the homeostasis of beta-carotene.
The American journal of clinical nutrition  •  1997  |  View Paper
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