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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ethanol and Benzoylecgonine



Research Papers that Mention the Interaction

Ethanol decreases the clearance of cocaine by inhibiting the hydrolysis of cocaine to benzoylecgonine and ecgonine methyl ester by carboxylesterases, and there is a large body of literature describing this interaction as it relates to the abuse of cocaine.
Drug Metabolism and Disposition  •  2010  |  View Paper
Ethanol pretreatment decreased benzoylecgonine concentrations in serum and liver.
Toxicology and applied pharmacology  •  1992  |  View Paper