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Last Updated: 3 years ago

Possible Interaction: Ethanol and Benzoylecgonine

supplement:

Ethanol

Research Papers that Mention the Interaction

Ethanol decreases the clearance of cocaine by inhibiting the hydrolysis of cocaine to benzoylecgonine and ecgonine methyl ester by carboxylesterases, and there is a large body of literature describing this interaction as it relates to the abuse of cocaine.
Drug Metabolism and Disposition  •  2010  |  View Paper
Ethanol pretreatment decreased benzoylecgonine concentrations in serum and liver.
Toxicology and applied pharmacology  •  1992  |  View Paper