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Last Updated: 3 months ago

Possible Interaction: Ethanol and Barbital

supplement:

Ethanol

Research Papers that Mention the Interaction

In this respect ethanol and barbital are probably related.
Psychopharmacologia  •  2004  |  View Paper
Barbital withdrawal signs were suppressed by pentobarbital, alcohol , chloroform, meprobamate, diazepam, chlordiazepoxide and oxazolam, but not by benzoctamine, perlapine or chlorpromazine.
The Journal of pharmacology and experimental therapeutics  •  1973  |  View Paper
However, cross-tolerance to barbital was observed after chronic treatment with ethanol.
Pharmacology Biochemistry and Behavior  •  1986  |  View Paper
Barbital pretreatment also prevents the ethanol induced inhibition of glycerol utilization, and α-glycerophosphate accumulation in liver.
Life sciences. Pt. 2: Biochemistry, general and molecular biology  •  1972  |  View Paper
Brain levels of barbital , phenobarbital, acetaldehyde, and acetone were increased by ethanol.
Induction time was shortened and sleeping time lengthened by the administration of ethanol with each of the five barbiturates, the effects being most pronounced with barbital and phenobarbital.
Canadian journal of physiology and pharmacology  •  1970  |  View Paper
The simultaneous administration of ethanol at doses of either 2, 3, or 4 g/kg intraperitoneally produced a dose-related decrease in the intraperitoneal LD50 for thiopentone, pentobarbitone, amylobarbitone, phenobarbitone and barbitone in rats.
The Journal of pharmacy and pharmacology  •  1970  |  View Paper
The simultaneous administration of ethanol at doses of either 2, 3, or 4 g/kg intraperitoneally produced a dose‐related decrease in the intraperitoneal LD50 for thiopentone, pentobarbitone, amylobarbitone, phenobarbitone and barbitone in rats.
The Journal of pharmacy and pharmacology  •  1969  |  View Paper
A study has also been made of the possible synergism between the action of barbitone and ethanol (on which conflicting reports have appeared (Gruber, 1955)) or 2-phenylethanol.
British journal of pharmacology and chemotherapy  •  1967  |  View Paper