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Last Updated: 7 months ago

Possible Interaction: Ethanol and Atipamezole

supplement:

Ethanol

Research Papers that Mention the Interaction

Atipamezole (3 mg/kg) attenuated the hypothermia induced by either ethanol (3 g/kg) alone or ethanol in combination with dexmedetomidine (0.3 mg/kg).
Atipamezole shortened the duration of the ethanol-impaired and ethanol + dexmedetomidine-impaired rotarod performance.
European journal of pharmacology  •  1995  |  View Paper
However, when coadministered with 2 g/kg ethanol, atipamezole (0.3-3.0 mg/kg) significantly attenuated the ethanol-induced reduction in the time spent in social interaction without any effect on ethanol's locomotor stimulant action.
Alcohol  •  1989  |  View Paper
When administered with ethanol (2 g/kg), atipamezole (1-3 mg/kg) showed a significant antagonism of the ethanol-induced reduction in exploratory head-dipping: no change in the locomotor stimulant properties of ethanol was seen.
Neuropharmacology  •  1989  |  View Paper