Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Ethanol and Aspartate

supplement:

Ethanol

Research Papers that Mention the Interaction

Closely associated with ethanol concentrations, supratentorial creatine, choline, inositol and aspartate levels decreased after ethanol administration, whereas glucose levels increased.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism  •  2009  |  View Paper
Acute exposure of ethanol reduces the level of glutamate and aspartate in cortical region.
Journal of neurochemistry  •  2014  |  View Paper
Ethanol (50 mM) significantly decreased the Vmax (2.2 +/- 0.2 microC for control vs. 1.6 +/- 0.2 microC for ethanol, n = 18, p < 0.05) of EAAT4 for L-aspartate.
Alcoholism, clinical and experimental research  •  2008  |  View Paper
This comparative analysis demonstrates that the ingestion of aspartate before the administration of alcohol dramatically decreases the aldehyde level in blood, and aspartate may be utilized as a prospective antagonist for acceleration of ethanol metabolism and prevention of acetaldehyde toxicity.
Journal of chromatography. B, Biomedical sciences and applications  •  1998  |  View Paper
Ethanol administration for 4 weeks significantly increased serum aspartate transaminase levels and hepatic pathology scores for steatosis, inflammation, and necrosis, as expected.
Hepatology  •  1997  |  View Paper
A bolus addition of 10 mM aspartate or 4 mM ammonia to cells metabolising lactate and ethanol were less effective than a steady-state low ammonia concentration, generated from urea/urease.
Biochimica et biophysica acta  •  1995  |  View Paper
K(+)-evoked release of glutamate and aspartate was inhibited by ethanol (25-100 mM) in a dose-dependent manner.
European journal of pharmacology  •  1992  |  View Paper
Moreover, Glu, but not Asp , effectively reversed the acute inhibition of steroidogenesis by ethanol.
Journal of steroid biochemistry  •  1989  |  View Paper
However, the K+-stimulated, Ca2+-dependent release of GABA, glutamate, and aspartate was significantly enhanced by ethanol for both the P and stock group of rats.
Alcoholism, clinical and experimental research  •  1986  |  View Paper
However, ethanol did enhance the K+-stimulated, Ca2+-dependent release of glutamate and aspartate from striatal slices to 168 and 214% of control values, respectively.
The release of glutamate and aspartate from slices of midbrain (minus colliculi) was also increased by 250 mg% ethanol.
Brain Research Bulletin  •  1985  |  View Paper
Show More