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Last Updated: 4 months ago

Possible Interaction: Ethanol and Asparagine

supplement:

Ethanol

supplement:

Asparagine

Research Papers that Mention the Interaction

However, the … effects of ethanol were reduced by expression of an NR1 C0 domain deletion mutant (NR1(Delta839-863)), truncation mutant (NR1(858stop)), or a triple-point mutant (Arg to Ala, Lys to Ala, and Asn to Ala at 859-861) previously shown to significantly reduce calcium-dependent inactivation.
The Journal of biological chemistry  •  2000  |  View Paper
In addition, trichloroethylene and N ,N-dimethylformamide cause intolerance of alcohol with hyperacetaldehydemia; acetaldehyde is claimed to be carcinogenic as well.
The Science of the total environment  •  1991  |  View Paper
Asparagine enhanced the rate of lactate-stimulated ethanol oxidation , particularly during the early part of the incubation.
Our studies suggest that asparagine or a low concentration of ammonia, by providing components of the malate/aspartate shuttle, can ameliorate some of the metabolic effects of ethanol on the liver.
The presence of asparagine also rapidly lowered the [lactate]/[pyruvate] ratio of hepatocytes incubated with lactate plus ethanol establishing a steady-state level of 15:1 within 10-15 min.
Biochimica et biophysica acta  •  1995  |  View Paper
In hepatocytes from fed rats alanine, asparagine , cysteine, glycine, hydroxyproline, ornithine and serine still increase ethanol oxidation, although to a lesser extent than in cells from starved rats.
In hepatocytes from starved rats, asparagine , serine, ornithine, hydroxyproline, histidine, cysteine, alanine, glycine, glutamate, glutamine, aspartate and arginine significantly increase ethanol consumption.
Advances in experimental medicine and biology  •  1980  |  View Paper
In hepatocytes from fasted rats, alanine, arginine, asparagine , aspartate, citrulline, cysteine, glutamate, glutamine, glycine, histidine, hydroxyproline, ornithine and serine increase significantly ethanol consumption.
Archives internationales de physiologie et de biochimie  •  1979  |  View Paper
By contrast the feeding of ethanol for a period of 6 months resulted in increases in the total activities of β-glucuronidase, β - N -acetylglucosaminidase and arylsulfatase A measured in the homogenates, and in the specific activities of these enzymes plus acid phosphatase measured in the lysosomal fraction.
Biochemical pharmacology  •  1976  |  View Paper
The … that L-asparagine prevents the decrease in hepatic ATP produced by each of these agents and protects against the fatty infiltration of the liver that … the administration of ethionine or small doses of CCl 4 , but not against that produced by large doses of CCl 4 or ethanol.
Biochemical pharmacology  •  1968  |  View Paper